Luigs & Neumann GmbH, 65 Years Of Innovation And Creativity

Precision, Customisation, And Reliability Are Our Goals

LN-PCS

Pipette cleaning system for up to 12 recording electrodes using air pressure system in combination with ultrasound

InVivo Neuro Pixels

The newly designed stand for the revolutionary Neuropixels probes allows changing the approach angle without losing the target area. Superb stability and flexibility round up the system.

LNscope

The LNscope can be adapted to any existing application due to its flexible design. The modular design enables the integration of various optics from different brands.

Micromanipulators

Positioning systems for electrophysiology, injection, and bath chambers.

SM10 Remote Control Touch

The new user experience in controlling electrophysiology rigs.

Multipatch

Multipatch Rig for up to 12 recording electrodes.

Multipatch System For Neuronal Networking

 

The newly designed system is using the full potential of the latest generation of our SM10 control system. The rigid platform prevents mechanical cross-talk between the recording electrodes. Up to 12 electrodes can be positioned around the specimen. Real-time automated positioning of the electrodes and unique ergonomic design simplifies your workflow.  

 

Multipatch system with 12 electrodes

The platform using 50 mm thick cast constructal aluminum

LN Junior Multipatch with fast exchange system and a small footprint with outstanding stability

All-new platform design with a T-slot

 
 
 

LNscope With Incredible Flexibility That Fits Your Demands

 

The modular design allows adaptation to any experimental application like Jet Ball, LNtreadmill, or InVitro.

 
 

 

Stainless steel frame prevents drift, vibration, and thermal expansion

Built-in 240 XY shifting table for increased stability

Dual objective holder with magnetic locking mechanism

 

LN Multiphoton LN-MPscope

 

LN Multiphoton Microscopy

In collaboration with Prof. Björn Kampa, RWTH Aachen

Flexibility

The revolutionary design allows you to modify the system by yourself. This system will grow with your needs.

 

Stability

The use of a cast airspace aluminum frame offers unmatched stability and light weight.

 

Courtesy of Prof. Kampa Lab, RWTH Aachen 2021

Visualize activity

We open the world of details for you.

cortical GCaMP expression mouse organotypic brain culture (40x optical + 2x digital magnification)

 

Fast, Easy Adaptation: Adjust height manually to fit both, in-vivo behavioral setups like jetballs or LN treadmills as well as in-vitro bath chambers.

Multi-Functional, Modular Design: Compatible with all common objective providers, epifluorescence heads, filters, as well as preferred PMTs and light sources. Due to its flexibility, this system will grow with your needs.

Precision Control: Equipped with high-quality, multiple decades approved LN micromanipulator technology for precise z-focus and XY table movement incorporates in our smart 3D steering system —ideal for delicate physiological experiments and precise imaging.

Unique optics: Ready for 2-/3-photon excitation with customizable laser and scanner configurations such as XY Galvos or high-speed resonance scanners, supporting a unique wide light pass (up to 50 mm) and extra-large field of view for mesoscopic objectives. All components selected for IR optimized wavelength.

Easy Imaging acquisition: Our system is equipped with powerful MBF Bioscience tools like the vDAQ™ card and a breakout box controlled via ScanImage ® software a cutting-edge microscope solution for synchronous, multiple device managment.

Engineered design meets function: A flexible dovetail system allows for easy adjustment of all key components while sleek and rigid design support flawless experiments with no distraction factors

 

The LN-MPscope is designed to offer scientists maximum adaptability and multifunctionality.

Newly Designed Positioning Stand For Neuropixels Probes.

 Readjust the approach angle without losing the targed area

InVivo brain accessibility new defined: Reach every coordinate of the mouse brain atlas and readjust the tissue entry angles of your probe in one simple twist at the manipulator stand while keeping the target destination stable

Double-sided and overhang (>90°) manipulator mount as well as offset-adapter usage provide a flexible toolset for delicate recordings in close proximity.

Overcome proximity issue: To master recordings in tightly connected brain regions (e.g. S1 and S2 cortex) we developed a variety of solutions: 1) A double-sided mount for two individually adjustable manipulator arms per stand, 2) an offset adapter offers the possibility to place electrodes on top of each other while controlled by separate arms.

Enhanced probe entry angle: The extended manipulator stand with an angle of up to 120° offers you an easy way to create less lesion in the hemisphere of interest by varying the positioning from the probe from one hemisphere to the other. Additonally, this provides one more method to reach tightly conncted areas.

Set the heigth according to your needs or exchange the tabel for a behavioral setup like the LN treadmill

Platform to individually position the animal

Electrophysiological application in behavioral assays (LN treatmill)

Fast, Easy Adaptation: Approved, modular LN design for flexible and efficient changes of configurations and recording situation e.g. varying the number of probes or changing from a fixation frame on a table to a behavioral setup like the LN treadmill, jetballs, etc.

Precision Control: Compatible with the Mini Compact micromanipulator and the SM10 control unit for the best balance of stability and precision. The fast exchange system allows easy pre-positioning by using the adjustable stop.

Stand equipped with headstage and fast exchange rail

All angles are adjustable with scale for best reproducible results

Work with up to 9 Neuropixels probes

Multifunctional with increased usability: Adding headstage adapters the system can be transformed for other elctrophysiolgical applications. Our tension blockers offer you additional usage of your own rods and probe holders.

9+ Neuropixels probes can be mounted

 
 
 

Mini Compact InVivo

Our new Mini Compact InVivo - that’s what we call flexibility

 

We Develope And Manufacture Manipulators For 38 Years

 
 

Our LN Mini / Compact manipulator line offers outstanding performance in terms of resolution, drift, and stability

 

 
 
 

Mini 25 Unit, 3 axis manipulator with tilting element

Setup for vital brain slices

Mini 25 Units mounted on stainless steel columns, using the same material as for the LNscope to eliminate thermal drift.

SM10 Remote Control Touch

 

The ergonomically shaped all-in-one remote control offers automation solutions. The highly customizable remote enables you to save user settings as different profiles, position electrodes automatically using the 3D-lock function, and operating the whole OS with an easy and intuitive UI.

 

SM10 Remote Touch

SM10 Remote Control touch and the wireless SM10 Cube

Cube SM10 wireless with coated aluminum control wheels

 

The SM10 Touch keypad offers the 3D-lock function, which allows to position electrodes far from each other without any PC software.

 
 

The LN Treadmill For Behavioral Studies In Different Environments

The standard length of 1 m allows placing a variety of tactile stimulations onto the belt

Reward system for applying solution at any desired time point

Headholder Stand. Can be adjusted for tilting, rotating, and XYZ positioning

Virtual reality 3 monitor arrangement

Virtual reality 5 monitor arrangement